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Comment :

Type  MGI:General Description  homozygotes display a striking reduction in the electrophysiological responses of vomeronasal sensory neurons to synthetic and natural pheromones relative to wild-type and heterozygous control mice unlike control mice, homozygotes fail to respond to 2-heptanone at 10-7 M, and exhibit only a small response to 2-heptanone at 10-4 M; on average, the size of the electro-vomeronasogram (EVG) response to 2-heptanone at 10-4 M is reduced to ~25% of control mice unlike control mice, homozygotes fail to elicit a urine-evoked field potential at dilutions of urine of 1/105, while peak EVG responses to female or male urine, at dilutions of 1/102, are reduced to ~37% of wild-type mice