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Comment :

Type  MGI:General Description  mutants exhibit less paw-licking behavior (correlated with lowered pain sensitivity) in mutants compared with wild-type in response to subcutaneous injection of capsaicin or formalin intrathecal injection of histamine shortened the latency of the tail-flick test in null mice compared to wild-type; i.t. injection of a tachykinin NK1 receptor antagonist significantly inhibited histamine-related nociceptive behaviors in null mice