| Type | MGI:General | Description | B cells become activated when cultured with HEL protein and CD4 T cells from Tg(TcrHEL3A9)1Mmd transgenic mice B cells in this culture quickly upregulate CD44 and CD86 by 48 hours in culture, B cells are greatly enlarged as they undergo blastogenesis B cells cultured without the T cells initially upregulate activation markers but then die when HEL peptide is used in culture, some B cells increase expression of activation markers but do not form large blast cells |
