| Type | MGI:General | Description | homozygotes exhibit a pulmonary artery pressure that is 90% higher than that of wild-type mice at baseline, RV pressure is comparable to pulmonary artery pressure either in wild-type or mutant mice, indicating absence of pulmonary valvular defects chronic pulmonary hypertension does not appear to be secondary to LV dysfunction but results in marked RV hypertrophy |
