| Type | MGI:General | Description | develop signs of chronic polyarthritis including joint swelling, distortion of fore and hind paw morphology, impaired movement disease onset occurs at 12 days of age early signs include hyperplasia of the synovial membrane and the presence of polymorphonuclear infiltrates; progressing to pannus and fibrous tissue formation, subchondral bone erosion, and articular cartilage destruction both IgM and IgG are detected in arthritic joints |