| Type | MGI:General | Description | homozygous null embryos displayed a specific defect in vessel bifurcation at the chorioallantoic junction, leading to severe undervascularization in the placental labyrinth unlike the wild-type labyrinth, the mutant labyrinth was saturated with maternal blood sinuses and few fetal vessels were detected notably, trophoblast nuclei were evident in both wild-type and mutant labyrinth, and differentiation of the labyrinthine syncytiotrophoblasts appeared normal |