| Type | MGI:General | Description | transgenic mice immunized with PLP peptide or rMOG protein show accelerated onset of experimental autoimmune encephalitis (EAE) and exacerbated the neurological deficit to a maximal disease score of 4.9 vs 2.1 in nontransgenic littermate controls with adoptive transfer of PLP peptide specific SJL T cell lines which induce severe, often lethal EAE, disease onset occurs 3-4 days earlier than in nontransgenic littermates |