| Type | MGI:General | Description | myofibers undergo a transition from small, compacted areas resembling minicores in younger mice to nemaline-rod like inclusions in adults type 2 (fast) myofibers exhibit gross structural defects in myofibrillar organization; myofibrils vary greatly in thickness and there are numerous sites of splitting and thinning type 1 fiber hypotrophy/atrophy is detected in muscle fibers as early as 6 weeks of age |