| Type | MGI:General | Description | Increased dopamine release in dorsolateral striatal slices as measured by fast scan cyclic voltammetry; in heterozygote increase is less than in homozygote, but higher than in wild-type Decay time of dopamine transient is slower in dorsolateral striatal slices Increased dopamine turnover as measured by ration of dopamine metabolites to dopamine In response to a D2 agonist, quinpirole, dorsolateral striatal slices exhibit a more rapid inhibition of dopamine release |
