| First Author | Roeder RG | Year | 1996 |
| Journal | Trends Biochem Sci | Volume | 21 |
| Issue | 9 | Pages | 327-35 |
| PubMed ID | 8870495 | Mgi Jnum | J:320280 |
| Mgi Id | MGI:6870981 | Citation | Roeder RG (1996) The role of general initiation factors in transcription by RNA polymerase II. Trends Biochem Sci 21(9):327-35 |
| abstractText | Transcription initiation on protein-encoding genes represents a major control point for gene expression in eukaryotes, and is mediated by RNA polymerase II and a surprisingly complex array of general initiation factors (TFIIA, -B, -D, -E, -F and -H) that are highly conserved from yeast to man. Elucidation of structural and functional features of these factors on model promoters has revealed insights into biochemical mechanisms and provides a basis for understanding their regulation on diverse promoters by gene- and cell-specific activators. |
