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Publication : Cancer as a complex genetic trait: tumor susceptibility in humans and mouse models.

First Author  Balmain A Year  2002
Journal  Cell Volume  108
Issue  2 Pages  145-52
PubMed ID  11832205 Mgi Jnum  J:74360
Mgi Id  MGI:2158160 Doi  10.1016/s0092-8674(02)00622-0
Citation  Balmain A (2002) Cancer as a complex genetic trait. Tumor susceptibility in humans and mouse models. Cell 108(2):145-52
abstractText  Cancer directly affects at least one-third of the human population, but the inherited genetic determinants of cancer risk remain largely unknown. Mouse models of human cancer are helping us to understand this disease as a complex genetic trait and thus to identify the multiple genetic variant alleles involved in pathways that affect individual cancer susceptibility.
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