First Author | Balmain A | Year | 2002 |
Journal | Cell | Volume | 108 |
Issue | 2 | Pages | 145-52 |
PubMed ID | 11832205 | Mgi Jnum | J:74360 |
Mgi Id | MGI:2158160 | Doi | 10.1016/s0092-8674(02)00622-0 |
Citation | Balmain A (2002) Cancer as a complex genetic trait. Tumor susceptibility in humans and mouse models. Cell 108(2):145-52 |
abstractText | Cancer directly affects at least one-third of the human population, but the inherited genetic determinants of cancer risk remain largely unknown. Mouse models of human cancer are helping us to understand this disease as a complex genetic trait and thus to identify the multiple genetic variant alleles involved in pathways that affect individual cancer susceptibility. |