First Author | Anderson KV | Year | 2000 |
Journal | Trends Genet | Volume | 16 |
Issue | 3 | Pages | 99-102 |
PubMed ID | 10689347 | Mgi Jnum | J:60745 |
Mgi Id | MGI:1353856 | Doi | 10.1016/s0168-9525(99)01921-6 |
Citation | Anderson KV (2000) Finding the genes that direct mammalian development : ENU mutagenesis in the mouse. Trends Genet 16(3):99-102 |
abstractText | The genetic control of mammalian embryogenesis is not well understood. N-ethyl-N-nitrosourea (ENU) mutagenesis screens in the mouse provide a route to identify more of the genes that are required for mammalian development. The characterization of ENU-induced mutations can build on the resources provided by the mouse and human genome projects to help define the tissue interactions and signaling pathways that direct early mammalian development. |