| First Author | Potter M | Year | 2000 |
| Journal | Curr Top Microbiol Immunol | Volume | 252 |
| Pages | 265-71 | PubMed ID | 11125484 |
| Mgi Jnum | J:67122 | Mgi Id | MGI:1929910 |
| Doi | 10.1007/978-3-642-57284-5_27 | Citation | Potter M, et al. (2000) Myeloma proteins that bind Hsp65 (GroEL) are polyreactive and are found in high incidence in pristine induced plasmacytomas. Curr Top Microbiol Immunol 252:265-71 |
| abstractText | The myeloma proteins produced by 44 plasmacytomas (PCTs) recently induced by pristane in BALB/cAnPt and closely related PCT susceptible congenic strains of mice were isolated chromatographically and screened against a panel of 10 protein, nucleic acid and lipid antigens. This sample was highly unusual because 82% of the proteins had IgG isotopes. Nine of the proteins bound to Hsp65 (GroEL), and all of these were polyreactative. Twenty-one of the myeloma proteins were polyreactive and bound two or more antigens in the panel, and five were monoreactive. Thus, an antigen binding activity was determined for 59% of these myeloma proteins. |
