First Author | Karolyi J | Year | 1988 |
Journal | Teratology | Volume | 37 |
Issue | 3 | Pages | 283-7 |
PubMed ID | 2966993 | Mgi Jnum | J:9180 |
Mgi Id | MGI:57643 | Doi | 10.1002/tera.1420370314 |
Citation | Karolyi J, et al. (1988) Genetics of susceptibility to 6-aminonicotinamide-induced cleft palate in the mouse: studies in congenic and recombinant inbred strains. Teratology 37(3):283-7 |
abstractText | In a search for genetic differences in susceptibility to cleft palate, congenic and recombinant inbred strains of mice were treated with 6-aminonicotinamide or control injections. Of six loci tested, only the chromosome segment marked by N-acetyl transferase was found to affect susceptibility to 6-aminonicotinamide-induced cleft palate. This chromosome segment is known to affect glucocorticoid-induced cleft palate and phenytoin-induced cleft lip with or without cleft palate in these strains of mice. |