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Publication : Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17.

First Author  Sertić J Year  1990
Journal  Genomics Volume  6
Issue  3 Pages  560-4
PubMed ID  1970332 Mgi Jnum  J:10445
Mgi Id  MGI:58896 Doi  10.1016/0888-7543(90)90487-f
Citation  Sertic J, et al. (1990) Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17. Genomics 6(3):560-4
abstractText  In humans, methylmalonyl acidemia is caused by a deficiency of L-methylmalonyl-CoA mutase (MUT) controlled by a gene that has been mapped to chromosome 6. The mouse homolog of this gene has now been mapped to mouse chromosome 17. Recombinant inbred and congenic strains place the mouse Mut locus 1.06 cM distal to H-2, between Pgk-2 and Ce-2. The relative order of syntenic probes flanking H-2 on mouse chromosome 17 and HLA on human chromosome 6 is shown to be different.
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