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Publication : Dosage of the Sts gene in the mouse.

First Author  Keitges E Year  1986
Journal  Am J Hum Genet Volume  39
Issue  4 Pages  470-6
PubMed ID  3464202 Mgi Jnum  J:15309
Mgi Id  MGI:63436 Citation  Keitges E, et al. (1986) Dosage of the Sts gene in the mouse. Am J Hum Genet 39(4):470-6
abstractText  In this study we compared steroid sulfatase levels in XO, XX, and XY mice and carried out a clonal analysis in fibroblast cell cultures from mice heterozygous for the steroid sulfatase deficiency gene and heterozygous at the X-linked electrophoretic phosphoglycerate kinase locus. The combined results indicate that the murine steroid sulfatase locus is not dosage compensated and is not subject to X-inactivation. With respect to X-inactivation, it behaves in a somewhat different way from the closely linked sex-reversed gene and the human steroid sulfatase locus.
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