First Author | Keitges E | Year | 1986 |
Journal | Am J Hum Genet | Volume | 39 |
Issue | 4 | Pages | 470-6 |
PubMed ID | 3464202 | Mgi Jnum | J:15309 |
Mgi Id | MGI:63436 | Citation | Keitges E, et al. (1986) Dosage of the Sts gene in the mouse. Am J Hum Genet 39(4):470-6 |
abstractText | In this study we compared steroid sulfatase levels in XO, XX, and XY mice and carried out a clonal analysis in fibroblast cell cultures from mice heterozygous for the steroid sulfatase deficiency gene and heterozygous at the X-linked electrophoretic phosphoglycerate kinase locus. The combined results indicate that the murine steroid sulfatase locus is not dosage compensated and is not subject to X-inactivation. With respect to X-inactivation, it behaves in a somewhat different way from the closely linked sex-reversed gene and the human steroid sulfatase locus. |