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Publication : Relationship between milk composition and pup's growth in mice.

First Author  Nagasawa H Year  1989
Journal  Proc Soc Exp Biol Med Volume  191
Issue  1 Pages  78-81
PubMed ID  2717628 Mgi Jnum  J:27645
Mgi Id  MGI:75134 Doi  10.3181/00379727-191-42892
Citation  Nagasawa H, et al. (1989) Relationship between milk composition and pup's growth in mice. Proc Soc Exp Biol Med 191(1):78-81
abstractText  The effect of lactation numbers (first, second, and third) on milk composition and the relationship between milk composition and pup's growth were examined in four strains of mice (SHN, SLN, C3H/He, and GR/A). Although the percentage of milk fat and moisture increased and decreased, respectively, through the first to third lactations in C3H/He mice, no differences in milk composition among lactation numbers were observed in the other mouse strains. In pooled data derived from the four strains of mice, there was no significant correlation between milk composition and body weight or growth rate of pups on Day 12 or 20 of the first lactation. In contrast, the amount of milk fat and moisture was the positively and negatively, respectively, correlated with the pup's growth parameters during the second and third lactations. This was reflected by a lower fat content and a higher moisture content in the milk of GR/A mice, especially evident during the second and third lactations and reduced pup's growth, when compared with the other mouse strains. Milk lactose and ash content was not correlated with pup's growth parameters. The results of our study stress the importance of milk fat for the growth of mouse pups.
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