First Author | Lloberas J | Year | 1999 |
Journal | Immunol Today | Volume | 20 |
Issue | 4 | Pages | 184-9 |
PubMed ID | 10203717 | Mgi Jnum | J:54032 |
Mgi Id | MGI:1334029 | Doi | 10.1016/s0167-5699(99)01442-5 |
Citation | Lloberas J, et al. (1999) The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages. Immunol Today 20(4):184-9 |
abstractText | PU.1 is a member of the transcription factor family Ets that is expressed selectively on B cells, myeloid cells and macrophages. PU.1 regulates the expression of several genes, including those encoding immunoglobulins, receptors and enzymes. The expression of these genes is crucial for macrophage and B-cell differentiation and for the functional activity of neutrophils. |