| First Author | Shefer VI | Year | 1997 |
| Journal | Exp Gerontol | Volume | 32 |
| Issue | 6 | Pages | 695-705 |
| PubMed ID | 9785095 | Mgi Jnum | J:44444 |
| Mgi Id | MGI:1100221 | Doi | 10.1016/s0531-5565(97)00085-5 |
| Citation | Shefer VI, et al. (1997) The effect of exercise training in a cold environment on thermoregulation in adult and aged C57BL/6J mice. Exp Gerontol 32(6):695-705 |
| abstractText | We studied the effect of exercise training in cold environment (six weeks of daily, one-hour runs on a treadmill at ambient temperature of 6 +/- 1 degrees C at 60-65% of VO2max) on cold-induced metabolic heat production, heat loss, and cold tolerance in adult and aged C57BL/6J male mice. In adult mice, exercise training in cold environment resulted in greater cold-induced heat production and cold tolerance without changes in heat loss, similar to the effects of daily cold exposure without exercise. In aged mice, daily cold exposures did not affect cold tolerance and cold-induced heat production, but exercise training in the cold resulted in greater cold-induced heat production and cold tolerance. Heat loss in aged mice increased similarly after both repeated cold exposures and exercise training in the cold. Therefore, mechanisms of effect of exercise training on cold tolerance are different in adult and aged animals. Exercise training in cold environment does not affect cold-induced heat production and cold tolerance in adult mice, but improves them in aged animals. |
