| Type | MGI:General | Description | transgenic mice show no neuronal loss or neuronal excitoxicity compared to wild-type controls, and in contrast to Tg(YAC128)53Hay mice at 12 months of age mice perform as well as wild-type mice in rotarod tests up to and including 10 months, and perform better than Tg(YAC128)53Hay mice at 2, 6, and 8 months mice perform better than Tg(YAC128)53Hay mice in open field tests at 2, 6, 8, and 10 months and are indistinguishable from wild-type controls, displaying no hypokinesia |
