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Comment :

Type  MGI:General Description  the number of corticospinal motor neurons is decreased at 10 and 18 months of age, but not at 3 months of age more than 60% of CTIP2-positive corticospinal motor neurons are lost in the motor cortex of 18 month old mice loss of corticospinal motor neurons in the cerebral cortex is selective, with no degeneration in layer V pyramidal neurons of the posterior cerebral cortex or in striatal medium spiny neurons