| Type | MGI:General | Description | 32% of mice develop a spontaneous form of arthritis between 20 and 50 weeks of age arthritis is characterized by severe ankylosis of the tibiotarsal and tarsophalangeal cartilage, loss of joint space and prominent periarticular new bone formation the arthritic joints contain synovial hyperplasia and proliferation, cartilage erosion, pannus formation, and joint space infiltrate |
