| First Author | Tarricone BJ | Year | 1995 |
| Journal | Behav Genet | Volume | 25 |
| Issue | 5 | Pages | 489-95 |
| PubMed ID | 7487846 | Mgi Jnum | J:28949 |
| Mgi Id | MGI:76486 | Doi | 10.1007/BF02253378 |
| Citation | Tarricone BJ, et al. (1995) Quantitative trait loci associated with the behavioral response of B x D recombinant inbred mice to restraint stress: a preliminary communication. Behav Genet 25(5):489-95 |
| abstractText | Quantitative trait loci (QTL) analysis was used to make provisional identification of loci containing genes influencing vulnerability to stress. The effect of restraint stress on open-field activity was measured in C57BL/6J and DBA/2J inbred strains of mice and in 22 B x D recombinant inbred strains of mice. QTL analyses were performed by correlating the behavioral delta scores for each group with the strain distribution pattern of 1300 markers for the B x D mice. A significant association was found between postrestraint rearings during min 5 through 8 in the open field and the Lamb2 marker on chromosome 1 (r = .718, p < .0001). Significant associations at the p < .0001 level were also found between baseline open-field rearings of control mice during min 0 through 5 and the Zp3, Ache, and Mr66-1 markers on chromosome 5, baseline open-field rearings of control mice during min 5 through 8 and the Pmv42 marker on chromosome 15, and open-field rearings of experimental mice during min 0 through 5 and the D11Ncvs61 marker on chromosome 11. |
