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Publication : VDAC2 (porin-2) expression pattern and localization in the bovine testis.

First Author  Hinsch KD Year  2001
Journal  Biochim Biophys Acta Volume  1518
Issue  3 Pages  329-33
PubMed ID  11311949 Mgi Jnum  J:69151
Mgi Id  MGI:1934109 Doi  10.1016/s0167-4781(01)00199-3
Citation  Hinsch KD, et al. (2001) VDAC2 (porin-2) expression pattern and localization in the bovine testis. Biochim Biophys Acta 1518(3):329-33
abstractText  In this study, sequencing of voltage-dependent anion channel 2 (VDAC2, porin-2) cDNA from bovine testis is reported. High identity to the murine, rabbit, and human subtypes at both the nucleotide and amino acid levels is demonstrated. mRNA analysis revealed expression of VDAC2 in bovine testis, whereas high levels of VDAC2 proteins were found in late spermatocytes, spermatids, and spermatozoa. In contrast, VDAC1 (porin-1) is exclusively localized in Sertoli cells. The possible role of testicular VDAC2 in providing energy metabolites and in germ cell apoptosis is discussed.
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