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Publication : Xath2, a bHLH gene expressed during a late transition stage of neurogenesis in the forebrain of Xenopus embryos.

First Author  Taelman V Year  2001
Journal  Mech Dev Volume  101
Issue  1-2 Pages  199-202
PubMed ID  11231075 Mgi Jnum  J:68161
Mgi Id  MGI:1932208 Doi  10.1016/s0925-4773(00)00546-3
Citation  Taelman V, et al. (2001) Xath2, a bHLH gene expressed during a late transition stage of neurogenesis in the forebrain of Xenopus embryos. Mech Dev 101(1-2):199-202
abstractText  We have identified a Xenopus bHLH gene, Xath2, which is the homologue of the murine MATH-2/NEX-1 gene, using a functional expression screening approach. Overexpression of this gene in neurula embryos induces the expression of the N-tubulin neuronal marker but does not stimulate the expression of the X-ngnr-1 and NeuroD proneural genes. Expression of Xath2 begins in stage 32 embryos and is restricted to the dorsal telencephalon. Within the neuroepithelium of the dorsal telencephalon, Xath2 expression is detected in postmitotic cells located more laterally than those expressing several other related bHLH neuronal regulators.
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