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Publication : Expression patterns of group-I aristaless-related genes during craniofacial and limb development.

First Author  Beverdam A Year  2001
Journal  Mech Dev Volume  107
Issue  1-2 Pages  163-7
PubMed ID  11520673 Mgi Jnum  J:71422
Mgi Id  MGI:2149939 Doi  10.1016/s0925-4773(01)00450-6
Citation  Beverdam A, et al. (2001) Expression patterns of group-I aristaless-related genes during craniofacial and limb development. Mech Dev 107(1-2):163-7
abstractText  Aristaless-related proteins are structurally defined by the presence of a paired-type homeodomain and an additional conserved domain, known as aristaless domain or OAR-domain. These proteins can be further categorized in three groups (Int. J. Dev. Biol., 43 (1999) 651). Group-I aristaless-related genes are linked to functions in the development of the craniofacial and appendicular skeleton and are expressed predominantly in the mesenchyme in stages from gastrulation through at least mid-gestation (Mech. Dev., 48 (1994) 245; Mech. Dev., 52 (1995) 51; Development, 124 (1997) 3999; Dev. Biol., 199 (1998) 11; Development, 126 (1999) 495). In view of the highly redundant character of the functions of these genes in patterning craniofacial and limb structures, we found it important to directly compare their expression patterns at critical stages of craniofacial and limb development.
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