| First Author | Kobayashi S | Year | 2002 |
| Journal | Biochem Biophys Res Commun | Volume | 290 |
| Issue | 1 | Pages | 403-8 |
| PubMed ID | 11779183 | Mgi Jnum | J:73955 |
| Mgi Id | MGI:2157235 | Doi | 10.1006/bbrc.2001.6160 |
| Citation | Kobayashi S, et al. (2002) Paternal expression of a novel imprinted gene, Peg12/Frat3, in the mouse 7C region homologous to the Prader-Willi syndrome region. Biochem Biophys Res Commun 290(1):403-8 |
| abstractText | Paternally expressed imprinted genes (Pegs) were systematically screened by comparing gene expression profiles of parthenogenetic and normal fertilized embryos using an oligonucleotide array. A novel imprinted gene, Peg12/Frat3, was identified along with 10 previously known Pegs. Peg12/Frat3 is expressed primarily in embryonic stages and might be a positive regulator of the Wnt signaling pathway. It locates next to the Zfp127 imprinted gene in the mouse 7C region, which has syntenic homology to the human Prader-Willi syndrome region on chromosome 15q11-q13, indicating that this imprinted region extends to the telomeric side in the mouse. |