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Publication : A genetic dissection of the retinoid signalling pathway in the mouse.

First Author  Mark M Year  1999
Journal  Proc Nutr Soc Volume  58
Issue  3 Pages  609-13
PubMed ID  10604193 Mgi Jnum  J:59797
Mgi Id  MGI:1352167 Doi  10.1017/s0029665199000798
Citation  Mark M, et al. (1999) A genetic dissection of the retinoid signalling pathway in the mouse. Proc Nutr Soc 58(3):609-13
abstractText  To determine the functions of retinoic acid receptors RAR and RXR, we have systematically knocked-out their genes by homologous recombination in the embryonic stem cells and generated null-mutant mice. This approach has allowed us to perform a genetic dissection of the retinoic acid signalling pathway.
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