First Author | Rajan L | Year | 2000 |
Journal | J Virol | Volume | 74 |
Issue | 5 | Pages | 2466-71 |
PubMed ID | 10666282 | Mgi Jnum | J:60327 |
Mgi Id | MGI:1353173 | Doi | 10.1128/jvi.74.5.2466-2471.2000 |
Citation | Rajan L, et al. (2000) The c-myc locus is a common integration site in type B retrovirus-induced T-cell lymphomas. J Virol 74(5):2466-71 |
abstractText | Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell leukemias. TBLV insertions near the c-myc gene were detectable in 2 of 30 tumors tested, whereas 80% of the tumors showed c-myc overexpression. TBLV insertions on chromosome 15 (including a newly identified locus, Pad7) may cause c-myc overexpression by cis-acting effects at a distance. |