First Author | Sinn PL | Year | 2000 |
Journal | Regul Pept | Volume | 86 |
Issue | 1-3 | Pages | 77-82 |
PubMed ID | 10672905 | Mgi Jnum | J:60486 |
Mgi Id | MGI:1353367 | Doi | 10.1016/s0167-0115(99)00097-x |
Citation | Sinn PL, et al. (2000) Transgenic models as tools for studying the regulation of human renin expression. Regul Pept 86(1-3):77-82 |
abstractText | Transgenic mice and rats have become popular tools to study the regulation of gene expression and the consequences of protein over-production. Over the past decade, numerous transgenic models have been developed to study the mechanisms of human renin gene expression and the participation of the renin-angiotensin system in the development of hypertension. Herein we will provide an overview of what has been learned from the use of transgenic models for studying the human renin gene. |