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Publication : Transgenic models as tools for studying the regulation of human renin expression.

First Author  Sinn PL Year  2000
Journal  Regul Pept Volume  86
Issue  1-3 Pages  77-82
PubMed ID  10672905 Mgi Jnum  J:60486
Mgi Id  MGI:1353367 Doi  10.1016/s0167-0115(99)00097-x
Citation  Sinn PL, et al. (2000) Transgenic models as tools for studying the regulation of human renin expression. Regul Pept 86(1-3):77-82
abstractText  Transgenic mice and rats have become popular tools to study the regulation of gene expression and the consequences of protein over-production. Over the past decade, numerous transgenic models have been developed to study the mechanisms of human renin gene expression and the participation of the renin-angiotensin system in the development of hypertension. Herein we will provide an overview of what has been learned from the use of transgenic models for studying the human renin gene.
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