| First Author | Hatada EN | Year | 2000 |
| Journal | Curr Opin Immunol | Volume | 12 |
| Issue | 1 | Pages | 52-8 |
| PubMed ID | 10679399 | Mgi Jnum | J:60341 |
| Mgi Id | MGI:1353187 | Doi | 10.1016/s0952-7915(99)00050-3 |
| Citation | Hatada EN, et al. (2000) NF-kappaB and the innate immune response. Curr Opin Immunol 12(1):52-8 |
| abstractText | In the innate immune reaction, microbial pathogens activate phylogenetically conserved cellular signal transduction pathways that regulate the ubiquitous nuclear factor-kappaB (NFkappaB). NF-kappaB has pleiotropic functions in immunity; however, it is also critical for development and cellular survival. Many aspects of how the different pathways utilize a common kinase complex that ultimately activates NF-kappaB have been clarified by gene inactivation and biochemical analysis. |
