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Publication : The GDNF family ligands and receptors - implications for neural development.

First Author  Baloh RH Year  2000
Journal  Curr Opin Neurobiol Volume  10
Issue  1 Pages  103-10
PubMed ID  10679429 Mgi Jnum  J:60472
Mgi Id  MGI:1353353 Doi  10.1016/s0959-4388(99)00048-3
Citation  Baloh RH, et al. (2000) The GDNF family ligands and receptors - implications for neural development. Curr Opin Neurobiol 10(1):103-10
abstractText  The glial cell line derived neurotrophic factor (GDNF) family has recently been expanded to include four members, and the interactions between these neurotrophic factors and their unique receptor system is now beginning to be understood. Furthermore, analysis of mice lacking the genes for GDNF, neurturin, and their related receptors has confirmed the importance of these factors in neurodevelopment. The results of such analyses reveal numerous similarities and potential overlaps in the way the GDNF and the nerve growth factor (NGF) families regulate development of the peripheral nervous system.
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