| First Author | Tarsounas M | Year | 1999 |
| Journal | Cytogenet Cell Genet | Volume | 87 |
| Issue | 3-4 | Pages | 201-4 |
| PubMed ID | 10702668 | Mgi Jnum | J:60867 |
| Mgi Id | MGI:1354035 | Doi | 10.1159/000015467 |
| Citation | Tarsounas M, et al. (1999) Identification of the mouse beta'-COP Golgi component as a spermatocyte autoantigen in scleroderma and mapping of its gene Copb2 to mouse chromosome 9. Cytogenet Cell Genet 87(3-4):201-4 |
| abstractText | In an immunological screening of a mouse testicular cDNA library with a human CREST serum we isolated five overlapping cDNA clones encoding the mouse homolog of a Golgi coatomer complex protein (accession number AF043120), designated beta'-COP in bovine and p102 in humans. We generated antibodies against this protein which specifically recognize the Golgi apparatus of mouse spermatocytes. FISH analyses assigned the beta'-COP gene Copb2 to mouse Chromosome 9, region E3-F1. Our results demonstrate that CREST sera can contain antibody components against Golgi proteins as well as against nuclear proteins. Copyright 2000 S. Karger AG, Basel |
