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Publication : Transgenic studies in rats and mice on the osmotic regulation of vasopressin gene expression.

First Author  Murphy D Year  2000
Journal  Exp Physiol Volume  85 Spec No
Pages  211S-222S PubMed ID  10795925
Mgi Jnum  J:62450 Mgi Id  MGI:1858889
Doi  10.1111/j.1469-445x.2000.tb00026.x Citation  Murphy D, et al. (2000) Transgenic studies in rats and mice on the osmotic regulation of vasopressin gene expression. Exp Physiol 85 Spec No:211S-222S
abstractText  Over the past 10-15 years, profoundly important transgenic techniques have been developed that enable new genes to be introduced into whole mammalian organisms. This review describes the ways in which transgenic animals, both rats and mice, have been used to study the mechanisms by which the expression of the vasopressin gene is confined to specific neurones in the hypothalamus, and how the pattern of that expression is altered following an osmotic challenge to the organism.
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