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Publication : Molecular cloning of the murine PHEX gene promoter.

First Author  Hines ER Year  2000
Journal  Biochim Biophys Acta Volume  1493
Issue  3 Pages  333-6
PubMed ID  11018258 Mgi Jnum  J:65004
Mgi Id  MGI:1891567 Doi  10.1016/s0167-4781(00)00188-3
Citation  Hines ER, et al. (2000) Molecular cloning of the murine PHEX gene promoter(1). Biochim Biophys Acta 1493(3):333-6
abstractText  We report the novel cloning of the murine PHEX promoter, the gene that is mutated in X-linked hypophosphatemic rickets (XLH). Four promoter/reporter gene constructs, -133/+104, -542/+104, -1061/+104, and -2866/+104, showed significant luciferase activity (4.9-13. 2-fold over background) when transfected into rat osteogenic sarcoma (UMR-106) cells.
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