First Author | Mulder H | Year | 2000 |
Journal | Metabolism | Volume | 49 |
Issue | 12 | Pages | 1518-22 |
PubMed ID | 11145110 | Mgi Jnum | J:66276 |
Mgi Id | MGI:1928220 | Doi | 10.1053/meta.2000.18511 |
Citation | Mulder H, et al. (2000) Differential changes in islet amyloid polypeptide (amylin) and insulin mRNA expression after high-fat diet-induced insulin resistance in C57BL/6J mice. Metabolism 49(12):1518-22 |
abstractText | Islet amyloid, derived from islet amyloid polypeptide (IAPP or amylin), frequently occurs in type 2 diabetes. Availability of this peptide for amyloid formation may be enhanced by increased islet expression of IAPP. In the insulin resistant state, euglycemia is maintained by hypersecretion of insulin. Whether |