First Author | Peters J | Year | 1976 |
Journal | Biochem Genet | Volume | 14 |
Issue | 1-2 | Pages | 119-25 |
PubMed ID | 1259699 | Mgi Jnum | J:5630 |
Mgi Id | MGI:54107 | Doi | 10.1007/BF00484878 |
Citation | Peters J, et al. (1976) Polymorphism of esterase-10 in Mus musculus. Biochem Genet 14(1-2):119-25 |
abstractText | An esterase, esterase-10, in the house mouse, Mus musculus, is specific for esters of 4-methylumbelliferone and exhibits a polymorphism detectable by electrophoresis. Fifteen inbred strains and two outbred strains have been examined for this polymorphism, and two phenotypes, ES-10A and ES-10B, have been observed. Each phenotype manifests itself as a single band of enzyme activity, but under the electrophoretic conditions used the ES-10A phenotype has less anodal electrophoretic mobility than the ES-10B phenotype. In F1 hybrids (C3H/He/LacxC57BL/Gr) a third phenotype was observed, ES-10AB, consisting of three bands of enzyme activity, two of which correspond to the parental forms and the third with intermediate mobility. The triple-band pattern in the F1 hybrids indicates that esterase-10 is a dimeric enzyme protein. |