First Author | Taylor BA | Year | 1977 |
Journal | J Virol | Volume | 23 |
Issue | 1 | Pages | 106-9 |
PubMed ID | 196096 | Mgi Jnum | J:5852 |
Mgi Id | MGI:54329 | Doi | 10.1128/jvi.23.1.106-109.1977 |
Citation | Taylor BA, et al. (1977) Genetic studies of the Fv-1 locus of mice: linkage with Gpd-1 in recombinant inbred lines. J Virol 23(1):106-9 |
abstractText | Multiple recombinant inbred lines, derived from crosses between strains permissive to N-tropic murine leukemia viruses (Fv-1n) and strains permissive to B-tropic murine leukemia viruses (Fv-1b), have been characterized as to Fv-1 genotype and other chromosome 4 markers, including the closely linked hexose-6-phosphate dehydrogenase isozyme locus (Gpd-1). Only one recombinant between Fv-1 and Gpd-1 was found among 45 lines tested. On this basis, the distance between Fv-1 and Gpd-1 is estimated to be 0.6 centimorgans. None of the lines was either resistant or susceptible to both N- and B-tropic viruses. Nineteen other inbred strains, previously untested, were characterized as either Fv-1n or Fv-1b. |