| First Author | Watson J | Year | 1978 |
| Journal | J Immunol | Volume | 120 |
| Issue | 2 | Pages | 422-4 |
| PubMed ID | 202651 | Mgi Jnum | J:5919 |
| Mgi Id | MGI:54396 | Doi | 10.4049/jimmunol.120.2.422 |
| Citation | Watson J, et al. (1978) The genetic mapping of a defective LPS response gene in C3H/HeJ mice. J Immunol 120(2):422-4 |
| abstractText | The expression of a defective LPS response gene Lps and the major urinary protein (Mup-1) are concordantly inherited in backcross (C3H/HeJ x C57BL/6J)F1 x C3H/HeJ mice, indicating genetic linkage of these loci. Mup-1 is known to be linked to the brown coat color locus on chromosome 4 in mice; thus Lps can now be assigned to chromosome 4. A value of 0.06 +/- 0.02 has been estimated for the recombination frequency between Mup-1 and Lps. We have used the polysyndactyly (Ps) mutation further to localize Lps on chromosome 4. Lps is located between the Mup-1 and Ps loci. |
