First Author | O'Brien D | Year | 1978 |
Journal | Cytogenet Cell Genet | Volume | 21 |
Issue | 1-2 | Pages | 72-6 |
PubMed ID | 648198 | Mgi Jnum | J:5978 |
Mgi Id | MGI:54455 | Doi | 10.1159/000130879 |
Citation | O'Brien D, et al. (1978) Assignment of the gene for lactic dehydrogenase A to mouse chromosome 7 using mouse-human hybrids. Cytogenet Cell Genet 21(1-2):72-6 |
abstractText | We have studied somatic cell hybrids between either mouse peritoneal macrophages or spleen cells and HT-1080-6TG human fibrosarcoma cells for the expression of mouse lactic dehydrogenase A (LDH-A). The hybrids were also studied for the expression of mouse glucose phosphate isomerase (GPI-1), the gene for which has been assigned to chromosome 7. Concordant segregation of the expression of mouse GPI-1 and LDH-1 was observed in 61 independent hybrid clones. These results indicate that the gene coding for LDH-A is located on mouse chromosome 7. |