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Publication : Genetic mapping of the ecotropic murine leukemia virus-inducing locus of BALB/c mouse to chromosome 5.

First Author  Kozak CA Year  1979
Journal  Science Volume  204
Issue  4388 Pages  69-71
PubMed ID  219475 Mgi Jnum  J:6116
Mgi Id  MGI:54593 Doi  10.1126/science.219475
Citation  Kozak CA, et al. (1979) Genetic mapping of the ecotropic murine leukemia virus-inducing locus of BALB/c mouse to chromosome 5. Science 204(4388):69-71
abstractText  By means of an approach that combined the techniques of somatic cell genetics and Mendelian breeding studies, the inducibility locus, designated Cv, for ecotropic murine leukemia virus in BALB/c mice, was mapped to chromosome 5, 23 units from the locus for phosphoglucomutase-1, with gene order Cv-Pgm-1-Gus. This low-efficiency inducibility locus is therefore not allelic with the chromosome 7 loci previously described for two other mouse strains with high virus inducibility. These studies provide further evidence that endogenous ecotropic viruses represent viral genomes inserted at different chromosomal sites in the various mouse strains.
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