First Author | Robinson PJ | Year | 1981 |
Journal | Proc Natl Acad Sci U S A | Volume | 78 |
Issue | 2 | Pages | 1167-70 |
PubMed ID | 6165007 | Mgi Jnum | J:19705 |
Mgi Id | MGI:67841 | Doi | 10.1073/pnas.78.2.1167 |
Citation | Robinson PJ, et al. (1981) Two allelic forms of mouse beta 2-microglobulin. Proc Natl Acad Sci U S A 78(2):1167-70 |
abstractText | Two allelic forms of mouse beta 2-microglobulin (beta 2m), the small polypeptide chain of H-2 histocompatibility antigens, have been identified. The two forms can be distinguished by NaDodSO4/polyacrylamide gel electrophoresis. All inbred mouse strains express a single beta 2m isotype. Mice heterozygous for beta 2m synthesize both forms, showing codominant expression of beta 2m alleles. In mice heterozygous for both H-2 and beta 3m, individual H-2 histocompatibility antigens associate with both beta 2m forms. Preliminary structural studies indicate differences in peptide composition between the two forms. |