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Publication : Two allelic forms of mouse beta 2-microglobulin.

First Author  Robinson PJ Year  1981
Journal  Proc Natl Acad Sci U S A Volume  78
Issue  2 Pages  1167-70
PubMed ID  6165007 Mgi Jnum  J:19705
Mgi Id  MGI:67841 Doi  10.1073/pnas.78.2.1167
Citation  Robinson PJ, et al. (1981) Two allelic forms of mouse beta 2-microglobulin. Proc Natl Acad Sci U S A 78(2):1167-70
abstractText  Two allelic forms of mouse beta 2-microglobulin (beta 2m), the small polypeptide chain of H-2 histocompatibility antigens, have been identified. The two forms can be distinguished by NaDodSO4/polyacrylamide gel electrophoresis. All inbred mouse strains express a single beta 2m isotype. Mice heterozygous for beta 2m synthesize both forms, showing codominant expression of beta 2m alleles. In mice heterozygous for both H-2 and beta 3m, individual H-2 histocompatibility antigens associate with both beta 2m forms. Preliminary structural studies indicate differences in peptide composition between the two forms.
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