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Publication : Upg-2: a urinary pepsinogen variant located on chromosome 1 of the mouse.

First Author  Szymura JM Year  1982
Journal  Biochem Genet Volume  20
Issue  11-12 Pages  1211-9
PubMed ID  7165695 Mgi Jnum  J:7001
Mgi Id  MGI:55472 Doi  10.1007/BF00498944
Citation  Szymura JM, et al. (1982) Upg-2: a urinary pepsinogen variant located on chromosome 1 of the mouse. Biochem Genet 20(11-12):1211-9
abstractText  Acrylamide gel electrophoresis of mouse urine distinguishes two groups of pepsinogens, the fast-migrating group A and the slow-migrating group B. Inbred mouse strains fall into two categories with respect to group B pepsinogens, one expressing a single-banded and the other a double-banded phenotype. This variation is controlled by a single locus, urinary pepsinogen-2 or Upg-2, which has at least two alleles, Upg-2s and Upg-2d. Typing of recombinant inbred strains suggests that the location of the Upg-2 locus is on chromosome 1, in the vicinity of loci coding for other peptidases, namely, Pep-2 and Rnr, and of the Acf-1 locus.
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