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Publication : A cluster of repetitive elements within a 700 base pair region in the mouse genome.

First Author  Kalb VF Year  1983
Journal  Nucleic Acids Res Volume  11
Issue  7 Pages  2177-84
PubMed ID  6188111 Mgi Jnum  J:15752
Mgi Id  MGI:63866 Doi  10.1093/nar/11.7.2177
Citation  Kalb VF, et al. (1983) A cluster of repetitive elements within a 700 base pair region in the mouse genome. Nucleic Acids Res 11(7):2177-84
abstractText  Approximately 39% of the clones from a BALB/c mouse genomic library hybridized with polyadenylated cytoplasmic RNA extracted from anemic mouse spleen. The DNA sequence of a portion of one such clone revealed the presence of three repetitive sequence elements within a 700 bp span. All three elements contain putative RNA polymerase III control regions oriented in the same direction and oligo(dA) tracts at their 3' ends. The first element is a member of the murine B1 family. A comparison of this element with other B1 family members indicates that the B1 family can be divided into two subclasses based on commonly held base changes and deletions. The second element within this 700 bp region may be a member of a new murine Alu family. Its structure is analogous to other murine Alu-equivalent sequences with respect to overall length, the presence of a 3' oligo(dA) tract and putative RNA polymerase III control regions. The third element is a murine type 2 Alu-equivalent sequence.
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