First Author | Potter M | Year | 1983 |
Journal | Infect Immun | Volume | 40 |
Issue | 3 | Pages | 1234-5 |
PubMed ID | 6343242 | Mgi Jnum | J:39562 |
Mgi Id | MGI:86866 | Doi | 10.1128/iai.40.3.1234-1235.1983 |
Citation | Potter M, et al. (1983) A BALB/c congenic strain of mice that carries a genetic locus (Ityr) controlling resistance to intracellular parasites. Infect Immun 40(3):1234-5 |
abstractText | BALB/c.DBA/2 Idh-1b-Ityr-Pep-3b congenic mice were developed by introgressively backcrossing the Idh-1b and Pep-3b markers of DBA/2 mice onto the BALB/c pi mice. This introduced a 30-centimorgan chromosome 1 segment of DBA/2 chromatin that contained the Ityr gene. BALB/c.DBA/2 Idh-1b-Ityr-Pep-3b mice were resistant to in vivo infections by Salmonella typhimurium, Mycobacterium bovis, and Leishmania donovani. |