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Publication : A BALB/c congenic strain of mice that carries a genetic locus (Ityr) controlling resistance to intracellular parasites.

First Author  Potter M Year  1983
Journal  Infect Immun Volume  40
Issue  3 Pages  1234-5
PubMed ID  6343242 Mgi Jnum  J:39562
Mgi Id  MGI:86866 Doi  10.1128/iai.40.3.1234-1235.1983
Citation  Potter M, et al. (1983) A BALB/c congenic strain of mice that carries a genetic locus (Ityr) controlling resistance to intracellular parasites. Infect Immun 40(3):1234-5
abstractText  BALB/c.DBA/2 Idh-1b-Ityr-Pep-3b congenic mice were developed by introgressively backcrossing the Idh-1b and Pep-3b markers of DBA/2 mice onto the BALB/c pi mice. This introduced a 30-centimorgan chromosome 1 segment of DBA/2 chromatin that contained the Ityr gene. BALB/c.DBA/2 Idh-1b-Ityr-Pep-3b mice were resistant to in vivo infections by Salmonella typhimurium, Mycobacterium bovis, and Leishmania donovani.
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