| First Author | Waterfield MD | Year | 1983 |
| Journal | Nature | Volume | 304 |
| Issue | 5921 | Pages | 35-9 |
| PubMed ID | 6306471 | Mgi Jnum | J:7117 |
| Mgi Id | MGI:55588 | Doi | 10.1038/304035a0 |
| Citation | Waterfield MD, et al. (1983) Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus. Nature 304(5921):35-9 |
| abstractText | A partial amino acid sequence of human platelet-derived growth factor, the major mitogen in serum for cells of mesenchymal origin, has been determined. A region of 104 contiguous amino acids shows virtual identity with the predicted sequence of p28sis, the putative transforming protein of simian sarcoma virus (SSV). This similarity suggests a mechanism for transformation by SSV and other agents, involving expression of growth factors. |
