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Publication : Murine T cell receptor beta chain is encoded on chromosome 6.

First Author  Lee NE Year  1984
Journal  J Exp Med Volume  160
Issue  3 Pages  905-13
PubMed ID  6206194 Mgi Jnum  J:7557
Mgi Id  MGI:56027 Doi  10.1084/jem.160.3.905
Citation  Lee NE, et al. (1984) Murine T cell receptor beta chain is encoded on chromosome 6. J Exp Med 160(3):905-13
abstractText  Southern blot analysis of somatic cell hybrid lines indicates that the beta chain of the T cell receptor for antigen maps to chromosome 6 of the mouse. An experiment testing hybridization of the constant region of this gene to DNA from a hybrid cell line containing a translocation of chromosome 6 supports the localization of this gene to the proximal (centromeric) one-third of chromosome 6, in the same general region as the immunoglobulin kappa chain locus. This may be another indication of the shared evolutionary origins of the genes encoding both T and B cell antigen recognition.
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