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Publication : Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene.

First Author  Greenberg ME Year  1984
Journal  Nature Volume  311
Issue  5985 Pages  433-8
PubMed ID  6090941 Mgi Jnum  J:7598
Mgi Id  MGI:56067 Doi  10.1038/311433a0
Citation  Greenberg ME, et al. (1984) Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311(5985):433-8
abstractText  Transcription of the c-fos proto-oncogene is greatly increased within minutes of administering purified growth factors to quiescent 3T3 cells. This stimulation is the most rapid transcriptional response to peptide growth factors yet described, and implies a role for c-fos in cell-cycle control. Transformation by c-fos may result from a temporal deregulation of this control.
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