| First Author | Shen-Ong GL | Year | 1984 |
| Journal | Science | Volume | 226 |
| Issue | 4678 | Pages | 1077-80 |
| PubMed ID | 6093260 | Mgi Jnum | J:7636 |
| Mgi Id | MGI:56105 | Doi | 10.1126/science.6093260 |
| Citation | Shen-Ong GL, et al. (1984) Activation of the c-myb locus by viral insertional mutagenesis in plasmacytoid lymphosarcomas. Science 226(4678):1077-80 |
| abstractText | Rearrangement in the c-myb locus of each of four independently derived BALB/c plasmacytoid lymphosarcoma (ABPL's) is due to the insertion of a defective Moloney murine leukemia virus (M-MuLV) into a 1.5-kilobase-pair stretch of cellular DNA at the 5' end of the v-myb-related sequences. This retroviral insertion is associated with abnormal transcription of myb sequences and probably represents a step in the neoplastic transformation of ABPL cells. |
