First Author | Shin HS | Year | 1984 |
Journal | Cell | Volume | 39 |
Issue | 3 Pt 2 | Pages | 573-8 |
PubMed ID | 6096010 | Mgi Jnum | J:7675 |
Mgi Id | MGI:56144 | Doi | 10.1016/0092-8674(84)90464-1 |
Citation | Shin HS, et al. (1984) Gene mapping within the T/t complex of the mouse. IV: The inverted MHC is intermingled with several t-lethal genes. Cell 39(3 Pt 2):573-8 |
abstractText | Using a combination of classical genetics, serology, and molecular genetics, we have mapped as many as possible of the MHC components in t haplotypes. Results indicate that the whole MHC is included in a simple inversion with the relative positions of its genes being intact. Furthermore, some of the t-lethal mutations map very near to, or are intermingled with, components of the MHC. At the centromeric end the t12 lethal maps between TL and H-2D in the Qa region, and distally the tw5 lethal is inseparable from H-2K. |