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Publication : Gene mapping within the T/t complex of the mouse. IV: The inverted MHC is intermingled with several t-lethal genes.

First Author  Shin HS Year  1984
Journal  Cell Volume  39
Issue  3 Pt 2 Pages  573-8
PubMed ID  6096010 Mgi Jnum  J:7675
Mgi Id  MGI:56144 Doi  10.1016/0092-8674(84)90464-1
Citation  Shin HS, et al. (1984) Gene mapping within the T/t complex of the mouse. IV: The inverted MHC is intermingled with several t-lethal genes. Cell 39(3 Pt 2):573-8
abstractText  Using a combination of classical genetics, serology, and molecular genetics, we have mapped as many as possible of the MHC components in t haplotypes. Results indicate that the whole MHC is included in a simple inversion with the relative positions of its genes being intact. Furthermore, some of the t-lethal mutations map very near to, or are intermingled with, components of the MHC. At the centromeric end the t12 lethal maps between TL and H-2D in the Qa region, and distally the tw5 lethal is inseparable from H-2K.
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